Scientific Research into Medicinal Cannabis – Diabetes
Diabetes is a chronic condition associated with abnormally high levels of sugar (glucose) in the blood. Insulin produced by the pancreas lowers blood glucose. Absence or insufficient production of insulin, or an inability of the body to properly use insulin causes diabetes.The two types of diabetes are referred to as type 1 and type 2. Former names for these conditions were insulin-dependent and non-insulin-dependent diabetes, or juvenile onset and adult onset diabetes.
We have listed the latest scientific research into medicinal cannabis and cannabidiol (CBD) and it’s potential uses treating Diabetes
- Cannabidiol protects retinal neurons by preserving glutamine synthetase activity in diabetes
- Decreased prevalence of diabetes in marijuana users: cross-sectional data from the National Health and Nutrition Examination Survey (NHANES) III
- The Impact of Marijuana Use on Glucose, Insulin, and Insulin Resistance among US Adults
- Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Pilot Study.
Is CBD oil good for diabetes?
The underlying factor in diabetes is insulin dysfunction, and cannabinoid receptors have been found in the islet cells of the pancreas that produce insulin. Intriguingly, the activation of CB1 receptors have been previously linked to insulin production.
According to Diabetes.co.uk
Chronic inflammation has long been known to play a key role in the development of insulin resistance and therefore type 2 diabetes. The researchers believe that the anti-inflammatory properties of CBD could treat this inflammation and therefore improve the body’s metabolism.
According to Israeli company Anananda Scientific
Chief Executive Officer Mark J. Rosenfeld said: “Phase 1 clinical trials on dosing and safety are now underway in Israel, and arrangements for Phase 2 trials on treating diabetes and chronic pain are in process.”
“Unlike insulin and other existing medications for diabetes, CBD may actually suppress, reverse and perhaps cure the disease,”
Dr. Raphael Mechoulam, the professor known for discovering cannabinol (CBD), also observed that CBD receptors are found throughout different parts of the body. While working with researchers at the Hebrew University of Jerusalem, he found that the therapeutic effects of CBD could be tailored to different endocannabinoid receptors in the body, including those in the pancreas. The pancreas regulates blood glucose levels, releasing insulin to combat high levels of blood glucose.
How can CBD help with diabetes?
Research has shown that:
- CBD can prevent against diabetic complications like atherosclerosis (build up of plaque in arteries), cell inflammation, and cell damage.
- CBD protected diabetic animals from incurring damage to their optic nerve by reducing neurotoxicity and inflammation.
- THCV, a secondary cannabinoid found in whole plant cannabis extracts, can reduce glucose intolerance, improve glucose tolerance, increase sensitivity to insulin, and improve triglyceride levels.
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