Scientific Research into Medicinal Cannabis – Cancer
Cancer refers to any one of a large number of diseases characterized by the development of abnormal cells that divide uncontrollably and have the ability to infiltrate and destroy normal body tissue. Cancer often has the ability to spread throughout your body.
Here you can find the latest scientific research into medicinal cannabis and cancer
- Cannabidiol inhibits growth and induces programmed cell death in kaposi sarcoma-associated herpes virus-infected endothelium
- Cannabidiol as potential anticancer drug
- Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1
- Cannabidiol inhibits angiogenesis by multiple mechanisms
- The inhibitory effects of cannabidiol on systemic malignant tumors
- Marijuana fights cancer and helps manage side effects
- In vitro and in vivo efficacy of non-psychoactive cannabidiol in neuroblastoma
- The Influence of Biomechanical Properties and Cannabinoids on Tumor Invasion
- Antitumorigenic targets of cannabinoids – current status and implications
- Cannabinoids – a new weapon against cancer?
- CBD, a novel inverse agonist for GPR12
- Cannabidiol enhances the inhibitory effects of delta9-THC on human glioblastoma cell proliferation and survival
- Antitumor effects of CBD, a nonpsychoactive cannabinoid, on human glioma cell lines
- Systematic review of the literature on clinical and experimental trials on the antitumor effects of cannabinoids in gliomas
- CBD inhibits human glioma cell migration through a cannabinoid receptor-independent mechanism
- Id-1 is a key transcriptional regulator of glioblastoma aggressiveness and a novel therapeutic target
- Triggering of the TRPV2 channel by cannabidiol sensitizes glioblastoma cells to cytotoxic chemotherapeutic agents
- CBD inhibits proliferation and invasion in U87–MG and T98G glioma cells through a multitarget effect
- Local delivery of cannabinoid-loaded microparticles inhibits tumor growth in a murine xenograft model of glioblastoma multiforme
- Synergistic responses between cannabidiol and DNA-damaging agents on the proliferation and viability of glioblastoma and neural progenitor cells in culture
- Cannabis improved survival of patients with aggressive brain cancer in controlled clinical study
- Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells
- Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis
- Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma
- Cannabidiol induces programmed cell death in breast cancer cells by coordinating the cross-talk between apoptosis and autophagy
- Cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration
- The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation
- Cannabinoids: a new hope for breast cancer therapy?
- Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition
- Anti-tumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma
- Crosstalk between chemokine receptor CXCR4 and cannabinoid receptor CB2 in modulating breast cancer growth and invasion.
- TRPV2 activation induces apoptotic cell death in human T24 bladder cancer cells: a potential therapeutic target for bladder cancer
Cancer Related Pain
- Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain
- Nabiximols for opioid-treated cancer patients with poorly-controlled chronic pain: a randomized, placebo-controlled, graded-dose trial
- Endocannabinoids in endocrine and related tumours
- A comparative study on CBD-induced apoptosis in murine thymocytes and EL-4 thymoma cells
- Anti-tumoral action of cannabinoids on hepatocellular carcinoma: role of AMPK-dependent activation of autophagy.
Leukemia & Blood
- Cannabidiol-induced apoptosis in human leukemia cells: A novel role of cannabidiol in the regulation of p22phox and Nox4 expression
- Delta9-tetrahydrocannabinol-induced apoptosis in Jurkat leukemia T cells is regulated by translocation of Bad to mitochondria.
- Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease.
- Cannabinoid Receptor-Mediated Apoptosis Induced by R(+)-Methanandamide and Win55,212-2 Is Associated with Ceramide Accumulation and p38 Activation in Mantle Cell Lymphoma
- Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1
- COX-2 and PPAR-γ confer cannabidiol-induced apoptosis of human lung cancer cells
- Decrease of plasminogen activator inhibitor-1 may contribute to the anti-invasive action of cannabidiol on human lung cancer cells
- Cannabinoid receptors, CB1 and CB2, as novel targets for inhibition of non-small cell lung cancer growth and metastasis.
- Δ9-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo
Mouth and Throat
- Cannabinoids Induce Apoptosis of Pancreatic Tumor Cells via Endoplasmic Reticulum Stress–Related Genes
Prostrate and Colon
- Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer
- Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent
- In Vitro Anticancer Activity of Plant-Derived Cannabidiol on Prostate Cancer Cell Lines
- Towards the use of non-psychoactive cannabinoids for prostate cancer
- Inhibition of colon carcinogenesis by a standardized Cannabis sativa extract with high content of cannabidiol
- Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: pro-apoptotic effects and underlying mechanisms.
- The role of cannabinoids in prostate cancer: Basic science perspective and potential clinical applications
- Anti-proliferative and apoptotic effects of anandamide in human prostatic cancer cell lines: implication of epidermal growth factor receptor down-regulation and ceramide production.
- Anticancer activity of anandamide in human cutaneous melanoma cells
- Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors.